Micellar solubilization of fatty acids in aqueous media containing bile salts and phospholipids

Smith, A.; Lough, A. K.

1. The solubility of fatty acids in aqueous media containing bile salts alone and in admixture with either lecithin (phosphatidylcholine) or phosphatidylethanolamine was determined. 2. Over the pH range 2-0-7-4, the order of fatty acid solubility in aqueous solutions containing bile salts was linoleic greater than oleic greater than elaidic greater than palmitic greater than stearic. The solubility of each fatty acid increased as the pH of the miceus solutions of bile salts greatly increased the solubility of palmitic acid and stearic acid. 4. In the presence of bile salts and lecithin, the solubility of oleic acid and elaidic acid decreased with increasing pH of the micellar solution, indicating a competitive effect between the fatty acid anions and lecithin. The solubility of linoleic acid increased linearly with lecithin concentration. 5. Phosphatidylethanolamine as an additive to bile salts increased the solubility of both saturated and unsaturated fatty acids in the pH range 2-3-7-4. The effectiveness of phosphatidylethanolamine as an amphiphile was similar to that of lecithin, although at pH 3.0 fatty acid solubility was greater in the presence of phosphatidylethanolamine. 6. The significance of these findings is discussed in relation to the intestinal absorption of fatty acids in sheep.
PMID: 1082

Jan 1976

Queries

Handapparate catalog - mediathek catalog - HGK catalog - Handapparate catalog - HGKplus

Full spec

DateAdded: 2016-09-23T10:46:07Z
DateModified: 2016-09-23T10:46:07Z
ISSN: 0007-1145
Issue: 1
JournalAbbreviation: Br. J. Nutr.
Key: B9WFUM66
Language: eng
LibraryCatalog: PubMed
Pages: 77-87
PublicationTitle: The British Journal of Nutrition
Volume: 35

- Handapparate

Micellar solubilization of fatty acids in aqueous media containing bile salts and phospholipids

Tags

Queries

Full spec

Agiles lernen: neue Rollen, Kompetenzen und Methoden im Unternehmenskontext

The Age of Spiritual Machines: When Computers Exceed Human Intelligence

Textures of The Anthropocene: Grain Vapor Ray

Deep learning and neural networks

ÜberSchrift

Visual studies : a skeptical introduction

I send you this cadmium red...: ein Briefwechsel über Farben

Zeichen : eine Einführung in die Semiotik für Grafikdesigner

Future perfect? : God, medicine and human identity

Das Detail in der Typografie : Buchstabe, Buchstabenabstand, Wort, Wortabstand, Zeile, Zeilenabstand, Kolumne : [eine kurz gefasste, prägnante Eröterung jener Fragen, die sich mit der Lesbarkeit von Texten befassen]

Micellar solubilization of fatty acids in aqueous media containing bile salts and phospholipids

Tags

Queries

Full spec

More from "Handapparate"

Agiles lernen: neue Rollen, Kompetenzen und Methoden im Unternehmenskontext

The Age of Spiritual Machines: When Computers Exceed Human Intelligence

Textures of The Anthropocene: Grain Vapor Ray

Deep learning and neural networks

ÜberSchrift

Visual studies : a skeptical introduction

I send you this cadmium red...: ein Briefwechsel über Farben

Zeichen : eine Einführung in die Semiotik für Grafikdesigner

Future perfect? : God, medicine and human identity

Das Detail in der Typografie : Buchstabe, Buchstabenabstand, Wort, Wortabstand, Zeile, Zeilenabstand, Kolumne : [eine kurz gefasste, prägnante Eröterung jener Fragen, die sich mit der Lesbarkeit von Texten befassen]